PE-22-28 10mg is supplied as one research vial for laboratory work involving short peptides and ion-channel biology. The 10mg marking identifies the nominal amount per vial; the 3ml marking on the illustration describes container capacity. The neuron and membrane graphic represents the research area. It does not demonstrate a physiological effect of the supplied material or establish its suitability for use in people.
PE-22-28 emerged from studies of shortened spadin analogues. A 2017 investigation identified a seven-amino-acid fragment and measured its effects on TREK-1, a potassium channel involved in membrane excitability. Electrophysiology experiments in a cell system expressing the channel found inhibitory activity. This provides a specific experimental basis for describing PE-22-28 as an ion-channel research peptide rather than assigning it a broad collection of untested effects.
The same publication investigated neuronal measurements and behavioral responses in mice. Such experiments can help researchers compare candidate molecules and explore relationships between channel activity and downstream biology. They do not establish antidepressant efficacy, a treatment schedule or safety in humans. Results also depend on the experimental system and the exact material used; observations from one study should not be treated as a guarantee for a separately supplied research lot.
The accompanying SRP chart summarizes the sequence from spadin-fragment research to TREK-1 inhibition and preclinical observations. Read it alongside the linked original publication for methods, controls and limitations. For any laboratory comparison, the supplied sequence and lot documentation should be checked against the study material. This listing does not certify biological potency or claim that the vial has been tested in those experiments. Product-specific analytical documentation will be added when the current-lot records are available.
Documentation status: The COA review, chromatography, mass-spectrometry and traceability graphics are educational examples, not test results for this product. For laboratory research use only; not for human or veterinary use, diagnosis or treatment.
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