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IGF-1 DES 1mg

Original price was: $89.99.Current price is: $80.99.

IGF-1 DES 1mg — one research vial. Currently out of stock. For laboratory research only; not for human or veterinary use.

Out of stock

IGF-1 DES 1mg is listed as a single research vial and is currently out of stock. This page retains the product information and research references for catalogue comparison; unavailable stock cannot be purchased. The DES designation matters because this material is distinct from IGF-1 LR3 and full-length IGF-1. The muscle-fiber and receptor illustration is a research motif and is not evidence of a localized muscle-growth effect.

Des(1-3) IGF-1 is an IGF-1 analogue lacking the first three amino acids. A 2001 cell study examined receptor activation using this analogue alongside other IGF forms. The work describes retained affinity for the type 1 IGF receptor with weaker affinity for IGF-binding proteins. This distinction makes the analogue useful in experiments that separate growth-factor receptor signaling from some aspects of extracellular binding-protein regulation.

The same study also found that IGF-binding protein-3 could inhibit receptor activation through a mechanism not explained solely by its affinity for the growth factor. That result is a useful caution against a simplified claim that reduced binding-protein affinity removes all regulation. Receptor phosphorylation, binding and downstream cellular measurements represent different endpoints. Their interpretation depends on the model and controls, and they do not establish a human dosing approach.

The shared SRP research card outlines truncation, receptor engagement and experimental cellular responses. The original paper is linked for direct review rather than replacing its methods with a promotional summary. Researchers should verify that the eventual supplied lot matches the intended analogue and relevant analytical specifications. The 1mg vial amount is not a recommended dose, and the label does not certify potency or purity.

Documentation status: The COA review, chromatography, mass-spectrometry and traceability graphics are educational examples, not test results for this product. For laboratory research use only; not for human or veterinary use, diagnosis or treatment.

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