Glutathione
Quick summary
A tripeptide (glutamate–cysteine–glycine) that is the cell's main thiol antioxidant. Research focus: redox balance and detoxification enzymes. This page leads with SRP's low-and-slow starting dose.
3D structure
Overview
A tripeptide (glutamate–cysteine–glycine) that is the cell's main thiol antioxidant.
Looking for research material? Simple Research Peptides lists Glutathione 1500 mg Vial for laboratory research use.
Mechanism
A thiol tripeptide that acts as the main cellular redox buffer and as a cofactor for glutathione peroxidases and transferases.
Research areas
- redox balance
- detoxification enzymes
Storage & reconstitution
Supplied as a freeze-dried (lyophilized) powder in a sealed vial. Unopened vials are generally kept cold and away from light. Labs usually reconstitute it with bacteriostatic or sterile water, letting the liquid run down the vial wall and swirling gently instead of shaking. The solution is then kept refrigerated.
Recommended starting dose (low and slow)
| Starting dose | Low end of the studied range: 100 mg; 100 mg. |
|---|---|
| Frequency | Reported schedules: 1–3x weekly. |
| Reconstitution | Examples: 600 mg vial + 3 mL bacteriostatic water = 200 mg/mL; 1500 mg vial + 5 mL water = 300 mg/mL. Different water volumes can be used; that only changes the draw volume, not the amount of peptide. storage note: Reconstituted: refrigerate, protect from light, use within 2–4 weeks. |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Top of the studied range: 200 mg; 200 mg. These are range tops, not verified ceilings. |
|---|
Route and timing
Route: Subcutaneous or intramuscular injection; IV use is described in clinical settings.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Short in the blood after injection (minutes).
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is Glutathione studied for?
In research it is studied for redox balance and detoxification enzymes. A thiol tripeptide that acts as the main cellular redox buffer and as a cofactor for glutathione peroxidases and transferases.
How is Glutathione given in research?
Subcutaneous or intramuscular injection; IV use is described in clinical settings. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
Related peptides
Last updated: October 19, 2026