SNAP-8 (Acetyl Octapeptide-3)
Quick summary
An eight-amino-acid version of the Argireline concept, studied in cosmetic formulation research. Research focus: SNARE complex research and cosmetic formulation science. This page leads with SRP's low-and-slow starting dose.
2D structure
Overview
An eight-amino-acid version of the Argireline concept, studied in cosmetic formulation research.
Looking for research material? Simple Research Peptides lists SNAP-8 10mg Research Peptide Vial for laboratory research use.
Mechanism
An extended version of the Argireline sequence with the same SNARE-competition mechanism.
Research areas
- SNARE complex research
- cosmetic formulation science
Storage & reconstitution
Supplied as a freeze-dried (lyophilized) powder in a sealed vial. Unopened vials are generally kept cold and away from light. Labs usually reconstitute it with bacteriostatic or sterile water, letting the liquid run down the vial wall and swirling gently instead of shaking. The solution is then kept refrigerated.
Recommended starting dose (low and slow)
| Starting dose | Low end of the studied range: 330 mcg. |
|---|---|
| Frequency | Reported schedules: 330–1000mcg daily (titrate). |
| Reconstitution | Examples: 10mg vial + 3mL diluent (as listed). |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Top of the studied range: 1 mg. These are range tops, not verified ceilings. |
|---|---|
| Step-up schedules reported | The amount is usually stepped up gradually ('titrated') but none of the ones read gives a step schedule. |
Route and timing
Route: Topical (applied to the skin).
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Not well characterized in published research.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: For topical use, usually none beyond a patch test; for injectable forms, CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is SNAP-8 (Acetyl Octapeptide-3) studied for?
In research it is studied for SNARE complex research and cosmetic formulation science. An extended version of the Argireline sequence with the same SNARE-competition mechanism.
How is SNAP-8 (Acetyl Octapeptide-3) given in research?
Topical (applied to the skin). See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
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Last updated: October 19, 2026