Selank
Also known as: TP-7, N-Acetyl Selank Amidate (modified form)
Quick summary
A synthetic seven-amino-acid peptide built from the immune peptide tuftsin with a short stabilizing tail added. Research focus: anxiety-related behavior in rodents, stress models and GABAergic modulation. This page leads with SRP's low-and-slow starting dose.
Amino acid sequence (one-letter code): TKPRPGP
Overview
A synthetic seven-amino-acid peptide built from the immune peptide tuftsin with a short stabilizing tail added. It was developed in Russia, and most papers study it in rodent models of anxiety and stress.
Looking for research material? Simple Research Peptides lists Selank 10 mg Neuroscience Research Peptide Vial for laboratory research use.
Mechanism
A stabilized analog of tuftsin. Studies suggest it affects GABAergic signaling and the breakdown of enkephalins.
Research areas
- anxiety-related behavior in rodents
- stress models
- GABAergic modulation
Storage & reconstitution
Typically supplied as a lyophilized powder; keep sealed vials cold (refrigerated short term, frozen for long-term holding) and away from light. Laboratories commonly reconstitute with bacteriostatic or sterile water, swirling gently rather than shaking, and keep the solution refrigerated, using it within a few weeks.
Recommended starting dose (low and slow)
| Starting dose | Subcutaneous example starts at 250-300 mcg once daily for weeks 1-2; starts at 200 mcg; at 250 mcg. |
|---|---|
| Frequency | Reported schedules: daily; Daily; Daily. |
| Reconstitution | Examples: 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL; 10 mg vial + 2 mL water = 5 mg/mL; 5mg vial + 2mL diluent (as listed). storage note: Reconstituted: refrigerate, used within 4 weeks. |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Conflict: stop at 500 mcg per day, headline range at 750 mcg, nasal course goes to 2,700 mcg/day. Injectable and nasal amounts are not interchangeable. |
|---|---|
| Step-up schedules reported | Subcutaneous example: 250-300 mcg daily weeks 1-2, 400-500 mcg weeks 3-4, then a 4-week break and a repeat at 300-500 mcg. For the nasal form it describes a 14-21 day course split into 2-3 sprays, then a 1-3 week break. |
Route and timing
Route: Intranasal or subcutaneous in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Short in the blood (minutes).
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is Selank studied for?
In research it is studied for anxiety-related behavior in rodents, stress models and GABAergic modulation. A stabilized analog of tuftsin.
How is Selank given in research?
Intranasal or subcutaneous in research protocols. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
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Last updated: October 19, 2026