Dihexa
Quick summary
A small-molecule analog of angiotensin IV that modulates the HGF/c-Met pathway, studied in synapse-formation models. Research focus: HGF/c-Met signaling and synaptogenesis. This page leads with SRP's low-and-slow starting dose.
2D structure
Overview
A small-molecule analog of angiotensin IV that modulates the HGF/c-Met pathway, studied in synapse-formation models.
Looking for research material? Simple Research Peptides lists Dihexa (5 mg Capsules, 30 Count) for laboratory research use.
Mechanism
An angiotensin-IV analog reported to strengthen HGF binding to its receptor c-Met.
Research areas
- HGF/c-Met signaling
- synaptogenesis
Storage & reconstitution
Supplied in capsule form. Store sealed in a cool, dry place away from light and moisture.
Recommended starting dose (low and slow)
| Starting dose | Low end of the studied range: Oral 10–30mg / topical 3–5mg daily (as listed, several routes). |
|---|---|
| Frequency | Reported schedules: Oral 10–30mg / topical 3–5mg daily. |
| Reconstitution | Pending - to be added by SRP |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Top of the studied range: Oral 10–30mg / topical 3–5mg daily (as listed, several routes). These are range tops, not verified ceilings. |
|---|
Route and timing
Route: Oral or topical in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Not well characterized in published research.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is Dihexa studied for?
In research it is studied for HGF/c-Met signaling and synaptogenesis. An angiotensin-IV analog reported to strengthen HGF binding to its receptor c-Met.
How is Dihexa given in research?
Oral or topical in research protocols. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
Related peptides
Last updated: October 19, 2026