TMG (Trimethylglycine)
Quick summary
Betaine, a methyl donor in the methionine–homocysteine cycle. Research focus: methylation and homocysteine metabolism. SRP's starting dose for this compound is still pending.
3D structure
Overview
Betaine, a methyl donor in the methionine–homocysteine cycle.
Looking for research material? Simple Research Peptides lists TMG Trimethylglycine 1500 mg per Serving – 240 Capsules for laboratory research use.
Mechanism
Donates a methyl group to homocysteine through the enzyme BHMT.
Research areas
- methylation
- homocysteine metabolism
Storage & reconstitution
Supplied in capsule form. Store sealed in a cool, dry place away from light and moisture.
Recommended starting dose (low and slow)
| Starting dose | Pending - to be added by SRP |
|---|---|
| Frequency | Pending - to be added by SRP |
| Reconstitution | Pending - to be added by SRP |
Route and timing
Route: Oral.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Not well characterized in published research.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only.
Frequently asked questions
What is TMG (Trimethylglycine) studied for?
In research it is studied for methylation and homocysteine metabolism. Donates a methyl group to homocysteine through the enzyme BHMT.
How is TMG (Trimethylglycine) given in research?
Oral. SRP has not yet published a frequency for this compound.
What amount should a researcher start with?
SRP has not yet published a starting dose for TMG (Trimethylglycine). Contact SRP before starting any research protocol, and do not guess.
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Last updated: October 19, 2026