Pinealon
Also known as: Glu-Asp-Arg, EDR peptide
Quick summary
A synthetic tripeptide (Glu-Asp-Arg) from the short-peptide bioregulator research tradition. Research focus: neuronal oxidative stress models and short-peptide bioregulators. This page leads with SRP's low-and-slow starting dose.
2D structure
Overview
A synthetic tripeptide (Glu-Asp-Arg) from the short-peptide bioregulator research tradition. Studies mostly look at it in cell and animal models of neuronal stress.
Looking for research material? Simple Research Peptides lists Pinealon (10 mg Vial) for laboratory research use.
Mechanism
A tripeptide (Glu-Asp-Arg) bioregulator. Cell studies suggest it can reach the nucleus and affect gene expression in nerve cells.
Research areas
- neuronal oxidative stress models
- short-peptide bioregulators
Storage & reconstitution
Typically supplied as a lyophilized powder; keep sealed vials cold (refrigerated short term, frozen for long-term holding) and away from light. Laboratories commonly reconstitute with bacteriostatic or sterile water, swirling gently rather than shaking, and keep the solution refrigerated, using it within a few weeks.
Recommended starting dose (low and slow)
| Starting dose | 1 mg once daily (agree; also lists an oral 0.2 mg twice daily form). |
|---|---|
| Frequency | Reported schedules: SubQ 1–2mg / oral 0.2mg BID daily. |
| Reconstitution | Examples: 20 mg vial + 3 mL water = 6.67 mg/mL; 10mg vial + 3mL diluent (as listed). |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | 2 mg per day (agree). |
|---|---|
| Step-up schedules reported | 20-day example: 1.0 mg daily days 1-5, 1.5 mg days 6-14, 2.0 mg days 15-20. |
Route and timing
Route: Subcutaneous injection after reconstitution is the route most often described in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Not well characterized in published research.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is Pinealon studied for?
In research it is studied for neuronal oxidative stress models and short-peptide bioregulators. A tripeptide (Glu-Asp-Arg) bioregulator.
How is Pinealon given in research?
Subcutaneous injection after reconstitution is the route most often described in research protocols. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
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Last updated: October 19, 2026