Obestatin
Quick summary
A peptide encoded by the same gene as ghrelin, studied for its own, sometimes opposing, effects on appetite and gut motility. Research focus: ghrelin gene products and appetite signaling. SRP's starting dose for this compound is still pending.
Amino acid sequence (one-letter code): FNAPFDVGIKLSGVQYQQHSQAL
Overview
A peptide encoded by the same gene as ghrelin, studied for its own, sometimes opposing, effects on appetite and gut motility.
Looking for research material? Simple Research Peptides lists Obestatin for laboratory research use.
Mechanism
Comes from the same gene as ghrelin. The receptor it acts through is still debated.
Research areas
- ghrelin gene products
- appetite signaling
Storage & reconstitution
Supplied as a freeze-dried (lyophilized) powder in a sealed vial. Unopened vials are generally kept cold and away from light. Labs usually reconstitute it with bacteriostatic or sterile water, letting the liquid run down the vial wall and swirling gently instead of shaking. The solution is then kept refrigerated.
Recommended starting dose (low and slow)
| Starting dose | Pending - to be added by SRP |
|---|---|
| Frequency | Pending - to be added by SRP |
| Reconstitution | Pending - to be added by SRP |
Route and timing
Route: Subcutaneous injection after reconstitution is the route most often described in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Not well characterized in published research.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks; fasting glucose, HbA1c and lipid panel; lipase where GLP-1 or amylin-pathway compounds are involved.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only.
Frequently asked questions
What is Obestatin studied for?
In research it is studied for ghrelin gene products and appetite signaling. Comes from the same gene as ghrelin.
How is Obestatin given in research?
Subcutaneous injection after reconstitution is the route most often described in research protocols. SRP has not yet published a frequency for this compound.
What amount should a researcher start with?
SRP has not yet published a starting dose for Obestatin. Contact SRP before starting any research protocol, and do not guess.
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Last updated: October 19, 2026