Hexarelin
Also known as: Examorelin
Quick summary
Hexarelin is a synthetic hexapeptide ghrelin-receptor agonist and a potent GH releaser in humans. Research focus: GH and ACTH secretion, pituitary reserve testing and cardiac GHS binding sites. This page leads with SRP's low-and-slow starting dose.
Amino acid sequence (one-letter code): HWAWFK
Overview
Hexarelin is a synthetic hexapeptide ghrelin-receptor agonist and a potent GH releaser in humans. It also binds a separate site in heart tissue (CD36), so it appears in cardiovascular research too.
Looking for research material? Simple Research Peptides lists Hexarelin 5mg Research Peptide Vial for laboratory research use.
Mechanism
A potent GHS-R1a agonist that also binds CD36 on heart tissue, a separate effect studied in cardiac models.
Research areas
- GH and ACTH secretion
- pituitary reserve testing
- cardiac GHS binding sites
Storage & reconstitution
Supplied as a lyophilized powder; keep sealed, dry and away from light, ideally frozen or refrigerated for long-term holding. Laboratories typically reconstitute with bacteriostatic or sterile water, swirling gently rather than shaking, then hold the solution refrigerated (2–8 °C) and use it within the window set by their own stability protocol.
Recommended starting dose (low and slow)
| Starting dose | Low end of the studied range: 100 mcg; 100 mcg; 100 mcg. |
|---|---|
| Frequency | Reported schedules: 1–3x daily; Daily. |
| Reconstitution | Examples: 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL; 2 mg vial + 2 mL water = 1 mg/mL. storage note: Reconstituted: refrigerate, used within 4 weeks. |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Top of the studied range: 200 mcg; 200 mcg; 200 mcg. These are range tops, not verified ceilings. |
|---|
Route and timing
Route: Subcutaneous injection after reconstitution is the route most often described in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: About 1 hour.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks; IGF-1, fasting glucose and HbA1c.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is Hexarelin studied for?
In research it is studied for GH and ACTH secretion, pituitary reserve testing and cardiac GHS binding sites. A potent GHS-R1a agonist that also binds CD36 on heart tissue, a separate effect studied in cardiac models.
How is Hexarelin given in research?
Subcutaneous injection after reconstitution is the route most often described in research protocols. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
Related peptides
Last updated: October 19, 2026