GHRP-2
Also known as: Pralmorelin, KP-102
Quick summary
GHRP-2 is a synthetic hexapeptide that activates the ghrelin (GHS-R1a) receptor. Research focus: ghrelin receptor agonism, GH secretory-burst dynamics and pituitary stimulation testing. This page leads with SRP's low-and-slow starting dose.
Amino acid sequence (one-letter code): AWAWFK
Overview
GHRP-2 is a synthetic hexapeptide that activates the ghrelin (GHS-R1a) receptor. It is one of the strongest GH releasers in its class. It also raises ACTH, cortisol and prolactin, and it has been used as a pituitary function test in Japan.
Looking for research material? Simple Research Peptides lists GHRP-2 (10 mg) Vial for laboratory research use.
Mechanism
A synthetic hexapeptide agonist of GHS-R1a that strongly releases growth hormone. It also raises prolactin and cortisol to some degree.
Research areas
- ghrelin receptor agonism
- GH secretory-burst dynamics
- pituitary stimulation testing
Storage & reconstitution
Supplied as a lyophilized powder; keep sealed, dry and away from light, ideally frozen or refrigerated for long-term holding. Laboratories typically reconstitute with bacteriostatic or sterile water, swirling gently rather than shaking, then hold the solution refrigerated (2–8 °C) and use it within the window set by their own stability protocol.
Recommended starting dose (low and slow)
| Starting dose | Low end of the studied range: 100 mcg; 100 mcg; 100 mcg; 100 mcg. |
|---|---|
| Frequency | Reported schedules: 1–3x daily; 100–300mcg 1–3x daily; 1–3× daily. |
| Reconstitution | Examples: 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL; 5 mg vial + 3 mL water = 1.67 mg/mL; 5mg vial + 2mL diluent (as listed). Different water volumes can be used; that only changes the draw volume, not the amount of peptide. storage note: Reconstituted: refrigerate, used within 4 weeks. |
Studied higher doses
Studies have used doses up to the amounts below. Higher doses can be dangerous. Whether a person can reach them safely depends on height, weight, activity level, training and pre-existing conditions. We recommend following the lower starting dose above, and contacting SRP with any questions.
| Highest amount reported in studies | Top of the studied range: 300 mcg; 275 mcg; 300 mcg; 300 mcg. These are range tops, not verified ceilings. |
|---|
Route and timing
Route: Subcutaneous injection after reconstitution is the route most often described in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Short, roughly 30 minutes to 1 hour.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks; IGF-1, fasting glucose and HbA1c.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is GHRP-2 studied for?
In research it is studied for ghrelin receptor agonism, GH secretory-burst dynamics and pituitary stimulation testing. A synthetic hexapeptide agonist of GHS-R1a that strongly releases growth hormone.
How is GHRP-2 given in research?
Subcutaneous injection after reconstitution is the route most often described in research protocols. See the dosing frequency block on this page for how often.
What amount should a researcher start with?
This page lists SRP's low-and-slow starting dose in the Recommended starting dose section. Higher amounts that appear in studies are listed separately with their safety context. Start with the lower dose and contact SRP with any questions.
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Last updated: October 19, 2026