ANP (Atrial Natriuretic Peptide)
Quick summary
A 28-amino-acid hormone released by heart muscle cells when they are stretched. Research focus: natriuretic peptide receptors, fluid and sodium balance and vascular tone. SRP's starting dose for this compound is still pending.
Overview
A 28-amino-acid hormone released by heart muscle cells when they are stretched. It is studied for its role in regulating sodium, fluid balance and vascular tone.
Looking for research material? Simple Research Peptides lists ANP 1 mg | Atrial Natriuretic Peptide for laboratory research use.
Mechanism
Binds the NPR-A receptor, raises cGMP and promotes salt excretion and blood-vessel relaxation.
Research areas
- natriuretic peptide receptors
- fluid and sodium balance
- vascular tone
Storage & reconstitution
Supplied as a freeze-dried (lyophilized) powder in a sealed vial. Unopened vials are generally kept cold and away from light. Labs usually reconstitute it with bacteriostatic or sterile water, letting the liquid run down the vial wall and swirling gently instead of shaking. The solution is then kept refrigerated.
Recommended starting dose (low and slow)
| Starting dose | Pending - to be added by SRP |
|---|---|
| Frequency | Pending - to be added by SRP |
| Reconstitution | Pending - to be added by SRP |
Route and timing
Route: Subcutaneous injection after reconstitution is the route most often described in research protocols.
Timing: Pending - to be added by SRP
Cycle length and repeat
Pending - to be added by SRP
Half-life
Approximate, for Bobby's review: Very short, a few minutes.
Side effects
Pending - to be added by SRP
Suggested bloodwork and monitoring
Draft, for Bobby's review: CBC and comprehensive metabolic panel (kidney and liver function, electrolytes) before starting and again after a few weeks; blood pressure and heart-rate records.
Cautions
Pending - to be added by SRP
Reconstitution calculator
Math aid only. It converts the numbers you enter; it is not dosing advice. For research use only. Prefilled with this page's vial size, reconstitution and low-and-slow starting dose where known; change any value.
Frequently asked questions
What is ANP (Atrial Natriuretic Peptide) studied for?
In research it is studied for natriuretic peptide receptors, fluid and sodium balance and vascular tone. Binds the NPR-A receptor, raises cGMP and promotes salt excretion and blood-vessel relaxation.
How is ANP (Atrial Natriuretic Peptide) given in research?
Subcutaneous injection after reconstitution is the route most often described in research protocols. SRP has not yet published a frequency for this compound.
What amount should a researcher start with?
SRP has not yet published a starting dose for ANP (Atrial Natriuretic Peptide). Contact SRP before starting any research protocol, and do not guess.
Related peptides
Last updated: October 19, 2026